ROLE OF NESFATIN-1 IN MAINTAINING CARBOHYDRATE HOMEOSTASIS IN HYPERTENSIVE PATIENTS
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.32, No. 32)Publication Date: 2016-12-30
Authors : M. O. Vizir; O. M. Kovalyova;
Page : 56-61
Keywords : nesfatin-1; insulin; hypertension; prediabetes; polymorbidity;
Abstract
The aim of this study is to analyze changes in the nesfatin-1 level in hypertensive patients depending on the carbohydrate profile parameters. 83 hypertensive patients aged 33 to 77 years were examined. Nesfatin-1 levels were determined by enzyme immunoassay method. Hypertensive patients have significantly higher levels of adipocytokine than healthy people. Results of data analyses may indicate a possible antihyperglycemic and insulinotropic effect of nesfatin-1 in hypertensive patients with normoglycemia or prediabetes. Confirmation of these processes requires a special study.
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