INTERLEUKIN-10 AND C-REACTIVE PROTEIN AS PROGNOSTIC MARKERS OF RECCURENT VASCULAR EVENTS AFTER ACUTE CORONARY SYNDROME
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.19, No. 19)Publication Date: 2010-06-30
Authors : N.P. Kopytsa; O.I. Lytvyn;
Page : 42-46
Keywords : acute coronary syndrome; C-reactive protein; interleukin-10; prognostic value; recurrent coronary events;
Abstract
Atherosclerotic plague destabilization is defined as strengthening of chronic inflammation process activity and is the reason of acute coronary syndrome (ACS). ACS manifests C-reactive protein (CRP) level increasing. In contrary, anti-inflammatory processes activate ? Interleukin-10 (IL-10) level increases. The aim of study was to determine prognostic value of CRP and IL-10 for the ACS outcomes in 6 month after coronary event. The aim realized with the assistance of the using the new coefficient of the reduction level IL-10. This coefficient allows to predict with high probability recurrent coronary events in patients after ACS.
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