SCREENING OF WILSON’S DISEASES EFFECT ON THE BRAIN AT EXON 8
Journal: International Journal of Neurology and Brain Disorders (Vol.2, No. 1)Publication Date: 2015-05-14
Authors : Vanita Pudata;
Page : 1-15
Keywords : Wilsonâ?™s Diseases; Exon 8; ATP7B gene;
Abstract
Wilson disease (WD) is an autosomal recessive disorder caused by defects in ATP7B gene located on chromosome 13q21.1, and manifested as Hepatolenticular degeneration as a result of accumulation of copper. A total number of 20 control samples were taken for studying the mutations in exon 8. Genomic DNA was prepared from the peripheral blood of the patients. The exon 8 was amplified by PCR using primers. Amplified DNA fragments were analyzed by Agarose gel electrophoresis. Further the patient PCR DNA products will be subjected to Restriction analysis. The results in all controls did not reveal any mutation in the exon 8 of the gene.
Other Latest Articles
- Bacteriological Quality Assessment of Some Locally Manufactured Dairy Desserts Sold in Beni-Suef City, Egypt and Molecular Detection of Staphylococcus aureus Enterotoxin Genes
- Some Immunomodulating Effects of Diclazuril in New Zealand Rabbits
- INTRACRANIAL PARASAGITTAL EPIDURAL ABSCESS: ANOTHER CONSIDERATION FOR THE ETIOLOGY OF ACUTE HEADACHE AND FEVER FOLLOWING A MINOR HEAD INJURY
- Studies on Beneficial Yeasts Isolated from Some Egyptian Dairy Products
- DO HUNTINGTON`S DISEASE PATIENTS BENEFIT FROM MULTIDISCIPLINARY INPATIENT REHABILITATION?
Last modified: 2017-01-09 19:44:32