ELECTRICAL CONTROL OF CANCER INVASION: A MINI REVIEW

Cancer metastasis, definded as the spread of cancer cells to distant organs, accounts for many cancer-related deaths. Migration is one of many factors implicated in this phenomenon. Mechanisms controling directional cancer invasion are not fully understood. Endogenous electric fields (EFs) have been demonstrated to be an important guidance cue controling directional cell migration. Indeed, many types of cancer cells migrate directionally in an EF. Understanding the electrical control of cancer invasion will help develop noval approaches to prevent cancer metastasis.