BLOOD LEVELS OF SUBSTANCE P AND BETA-ENDORFINS AND EXPERIMENTAL MYOCARDIAL INFARCTION CICATRISATION

The experiment over 30 dogs with myocardial infarction (MI) model shows that the blood dynamics ofmaintenance and balance of substance P (SP) and beta-endorphins (BE) are in compliance with MI cicatrisation outcomes. For the cicatrisation without compliances the CP predominance in the acute period and BEpredominance in the sub-acute period is typical. The CP predominance during the whole experiment appearsto be determinative for the complicated MI cicatrisation. Monitoring of the CP and BE levels can be considered as one of timely methods of diagnosing and healing of the complicated IM cicatrisation.