Reciprocal reactions to different amounts of increased breathihg resistance

Objective: to study the role of the components of the stress-realizing and stress-limiting body systems at adaptation to different values breathing resistance. Materials and Methods: The study was conducted on healthy individuals (126 men), aged 18 to 38 years old of both sexes. Inspiratory breathing applied resistive load value of 20, 40 and 60%Pmmax. We measured the performance of hemostasis, immunity, oxidative activity, stress hormones. Results: Inspiratory load 40%Pmmax leads to activation of the anticoagulating mechanisms, increase antioxidant activity, stress-limiting effects and immunosuppressive changes; load 60%Pmmax caused opposite effects. Conclusions: The increased breathing resistance 40%Pmmax activates the stress-limiting systems; resistive load 60%Pmmax causes activation reciprocally organized stress-implement systems.