THE EFFICACY AND SAFETY OF VARIOUS SCHEMES OF SYSTEMIC DRUG THROMBOLYSIS IN MYOCARDIAL INFARCTION WITH ST-SEGMENT ELEVATION IN SENILE PATIENTS
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.24, No. 4)Publication Date: 2016-12-30
Authors : D.S. Yunevich;
Page : 32-41
Keywords : myocardial infarction; senile age; thrombolytic therapy; alteplase; prourokinase; streptokinase. _____________________________________________________________________________;
Abstract
The results present the comparative analysis of the efficacy and safety of thrombolytic therapy with different drugs in 98 patients 75 years and older with myocardial infarction with ST-segment elevation. The prevalence of 28-day mortality was observed after the introduction of streptokinase compared to alteplase and prourokinase. Differences were noted in the levels of female mortality. The incidence of reperfusion arrhythmias was higher when we usеd alteplase compared to other thrombolytic drugs. The minimum number of side effects was observed with the introduction of prourokinase.
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