IMMUNE THROMBOCYTOPENIA AFTER ALLOGENEIC STEM CELL TRANSPLANTATION: CASE REPORT AND BRIEF OVERVIEW OF TREATMENT STRATEGIES
Journal: Journal of Hematology and Oncology Research (Vol.2, No. 3)Publication Date: 2016-06-29
Authors : Isacco Ferrarini; Gloria Turri; Dino Veneri; Cristina Tecchio; Achille Ambrosetti;
Page : 3-8
Keywords : LLeukemia; Allogeneic stem cell transplantation; Immune thrombocytopenia; Eltrombopag;
Abstract
Immune thrombocytopenia (ITP) is a rare but well-recognized post-allogeneic hematopoietic stem cell transplant (HSCT) autoimmune complication for which a standard treatment approach is lacking. Herein we report on an adult patient affected by high-risk acute myeloid leukemia (AML) who developed a post-HSCT ITP. Due to the refractoriness to first-line therapies the patient underwent the thrombopoietin (TPO) mimetic Eltrombopag obtaining the ITP resolution. We also discuss the clinical course of ITP in post-HSCT setting and pros and cons of different therapeutic strategies, focusing on the emerging role of TPO mimetics.
Other Latest Articles
- Acute Onset Symptomatic Polycythaemia Vera
- Current student periodicals typology
- Art imagery in Advertising in terms of socio-cultural transformations of XX ? XXI century
- Pedagogical activity of M. Rokitsky in the workshop of monumental painting of KAI. Features of an educational method of professional training
- The Ukrainian music ethnic culture through the prism of the student’s youth vision
Last modified: 2017-02-03 04:04:25