Antimicrobial Susceptibility Patterns of Gram Positive Isolates from Saudi Arabian Hospital

The study was carried out in Jazan general hospital of Saudi Arabia. The main focus lies in recovery of Staphylococcus aureus isolates from different places confined to the hospital to determine the chances of nosocomial infection and its susceptibility pattern against selected antibiotics. Total 332 cfu were observed at five different places viz. OPD, Emergency, Ward, Corridor, and thumb impression of ward attendants & technical staff. No cfu was observed in Operation Theater. Out of total 332 only 63 cfu were found typical of gram positive Staphylococcus aureus, which were analyzed for its phenotypic characteristic and antimicrobial susceptibility. The biochemical characterization was done by API 20E and five different biochemical patterns (I-V) were detected among isolates. They were found distributed in almost all the areas; however the most predominant of all i.e. biochemical patterns I was found in each area of the hospital. The isolates vary in its antibiotic susceptibility pattern. All isolates (100%) were found to be susceptible to Gatifloxacin, Ampicillin sulbactam, Ciprofloxacin and Sulphamethoxazole trimethoprime. Chloramphenicol and Cefotaxime sodium shows 95%, Ofloxacin 96%, Tetracycline 95%, Vancomycin, and Methicillin 93%, Cefactor 85%, Cefeprime 84%, Gentamycin 82%, Latmoxef 77% and Cefprozoil & Fusidic acid 74% susceptibility. However all isolates were found to be resistant to Bacitracin, Aztreonam, Azithromycin and Cefixime.