ANTI-HELICOBACTER PYLORI ACTIVITY OF THREE MEDICINAL PLANTS (CINNAMOMUM ZEYLANICUM, SYZYGIUM AROMATICUM AND ZINGIBER OFFICINALE)

In this study, three medicinal plants; cinnamon (Cinnamomum zeylanicum), clove (Syzygium aromaticum) and ginger (Zingiber officinale) extracts were examined and screened for anti-Helicobacter pylori activity. Ninety-six percent of methanol was used for the extraction of these plants. It has been shown that Zingiber officinale contains high total phenolic compounds content (110 mg GAE / 100 g extract) in comparison to Cinnamomum zeylanicum (98.2 mg GAE / 100 g extract) and Syzygium aromaticum (98 mg GAE / 100 g extract). The antioxidant activity of our extracts measured by FRAP method indicates that S. aromaticum had a high antioxidant activity (107.2 mg AAE / 100 g extract) relative to Z. officinale (105.1 mg AAE / 100 g extract) and C. zeylanicum (58 mg AAE / 100 g extract). All studied plants demonstrated strong anti-H. pylori activity with inhibition zone diameter ranged from 10 to 36 mm.