A case report of Hypogonadotropic hypogonadism associated with empty sella

We describe a 20 year old male who presented with complaints of failure to attain puberty, break in voice, underdeveloped genitalia and testicular atrophy. He had eunuchoid body proportions with a height of 150 cms and arm span of 157 cms, a lower segment of 84cms , a upper segment of 66cms. There was no anosmia or midline defects. MRI brain showed empty sella with ectopic posterior pituitary and CSF collection surrounding the gland. His laboratory investigations showed low luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Conclusion - Uncommon presentation of isolated gonadotropin deficiency secondary to pituitary cause leading to delayed puberty.