Study of outcome with twin dose antibiotic therapy in elective laparoscopic cholecystectomy

Introduction: Laparoscopic cholecystectomy offers increased safety in obese, decreased post operative pain, early initiation of enteral feeding, early ambulation, shorter hospital stay, decreased wound complications and improved quality of life. 95% of currently performed cholecystectomies are by Laparoscopic approach. Aim: The present study was designed to assess the role of double dose antibiotic therapy in elective laparoscopic cholecystectomy in Osmania General Hospital. Materials and methods: The present clinical study was a prospective study conducted at Osmania General Hospital Hyderabad, Andhra Pradesh. 30 patients were selected from a period of December 2011 to July 2013 undergoing elective endocystectomy according to inclusion and exclusion criteria. Results: A total of 30 LC were studied, out of which 5 developed adverse results with infection rate of 16.66%. In earlier year i.e. 2011, infection result rate is higher (25%) when compared to this year i.e. 2013 (11.76%). Infection result rate for 25-64 year group was 17.64%, for 65-70 year group was 15.38%. Out of 30 patients, 9 patients (30%) who had symptoms for less than 30 days in those 3 patients (33.33%) developed infection whereas 21 patients (70%) who had symptoms for more than 30 days 2 cases (9.5%) with infection are noted. Of the 5 cases that had developed adverse results, 2 patients suffered from pneumonia, 1 patient developed cholangitis, 1 patient developed peritonitis and 1 patient developed bile leak. Conclusion: Study found that the dual dose antibiotic therapy is effective in preventing the postoperative infection result.