EFFICIENCY OF PREVENTION OF COLD BRONCHIAL OBSTRUCTION AT PATIENTS WITH BRONCHIAL ASTHMA ASSOCIATED WITH COMORBID STATE UNDER THE CONDITIONS OF HIGH LATITUDES

The analysis of spirography indices, characterizing the efficiency of cold bronchial obstruction at smokers (n=22) and non-smokers (n=20) with bronchial asthma associated with chronic obstructive lung disease and arterial hypertension, was conducted including cold tests before and after preliminary application of Foradil Combi, Spiriva and Singulair. The more significant therapeutic effect was noted at non-smokers with bronchial asthma associated with comorbid state. It was found that the method of pharmacologic protection against cold bronchial obstruction had been highly efficient at patients with mixed pathology.