Extraction and Standardization of Anthelmintic Activity of Solanum Xanthocarpum

Solanum xanthocarpum (Solanaceae) is distributed all over India and has been used by triable as well a local people widely. Locally it is known as “Kantakari”. In present investigation the aim is to focus on the anthelmintic activity of this valuable medicinal plant Solanum xanthocarpum. Helminthiasis is a worldwide and one of the common diseases of all ages. As per WHO more than two billion people harbor this infection. From the survey of WHO only few drugs are frequently used in the treatment of helminthes in human, due to the cost and the development of resistance against these drugs. In the present work the alcoholic and aqueous extracts of Solanum xanthocarpum were evaluated for its anthelmintic activity against adult earthworms (Phertima prosthuma). The activities of the extracts were compared with standard Albendazole. Both the extracts and standard were prepared in saline water. The alcoholic and aqueous extract showed significant anthelmintic activity and it was found that the aqueous extract activity is higher than alcoholic extract.