Evaluation of Traditional Formulation for Anti-pyretic Activity in Milk Induce Pyrexia Model of Rabbits

A formulation of Andrographis paniculata is widely used by traditional healers for the treatment of fever in rural northern Karnataka. The present study was undertaken to evaluate the safety and efficacy of the formulation milk induced pyrexia model. After 1 hr intraperitonial administration of milk, decoction was given in the oral dose of 0.7 ml/kg, which, were shown to be significant in reducing reduced the elevated body temperature of rabbit.