PECULIARITIES OF PATHOGENESIS OF COMORBID ARTERIAL HYPERTENSION AND DIABETES MELLITUS 2 TYPE
Journal: Paradigmata poznání (Vol.4, No. 2)Publication Date: 2017-05-20
Authors : O. M. Bilovol; L. R. Bobronnikova;
Page : 56-61
Keywords : arterial hypertension; diabetes mellitus type 2; pathogenesis mechanisms of development; adipokines imbalance; gene polymorphism;
Abstract
In the article features of pathogenetic mechanisms of the combined course of arterial hypertension and type 2 diabetes mellitus are considered. This pathology potentiates the development of micro- and macrovascular complications, raises cardiovascular risk. Concomitant abdominal obesity contributes to the imbalance of adipocytokines, and complicates the course of type 2 diabetes. It was established that polymorphism of candidate genes associated with the development and progression of insulin resistance, which is of interest for further study
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