EVALUATION SOME OF IMMUNOLOGICAL PARAMETERS IN BENIGN PROSTATIC HYPERPLASIA PATIENTS TREATED WITH 5 ALPH-REDUCTASE INHIBITOR (FINASTERIDE)

In order to evaluate the levels of PSA, IL-17 ,and CRP in BPH patients, (60) BPH patients, and (30) healthy man as control group were involved in the current study ,their ages (the control and patients) were between (40-59) years old. All of them living in Amara city .Estimation of PSA,IL-17 and CRP in serum were achieves before and after 3 month of treatment by 5 -α reductase (finasteride) ,and the results shown that there were a significant decreased (P<0.01)in serum PSA in post-treatment group compared to pre-treatment , which was higher than control group .in addition ,IL-17 level was increased significantly (P<0.05)in comparison with post-treatment and control group , also the CRP level (positive) was increased in pre-treatment group compared to post-treatment and control group .In conclusion the BPH effect on level serum of PSA,IL-17 and CRP by significant increased, while the finasteride causes significant dcreased in theri levels after 3 month of treatment.