Structural, Optical and Antimicrobial Activity of Copper and Zinc Doped Hydroxyapatite Nanopowders using Sol-Gel Method

Antimicrobial materials based on hydroxyapatite nanopowders are functionally attractive in a wide variety of medical applications. The Cu2+ and Zn2+ incorporated HAp nanopowders were synthesized by simple Sol-Gel method. The structural study, optical study and biological activity of the prepared nanopowders were characterized by X-ray diffraction, UV-Vis absorption spectroscopy and disc diffusion method respectively. The XRD results are demonstrated that the presence of copper and zinc doped hydroxyapatite nanopowders and size of the crystalline was found for pure HAp, 10%, 25% and 50% of Zn2+/ Cu2+ metal ions incorporated HAp respectively. The optical absorption analysis was used to estimate band gap value of pure HAp 3.86eV and Zn2+/ Cu2+ doped HAp 3.77eV (10%), 3.69eV (25%) and 3.30eV (50%) respectively. Antibacterial activity of synthesized nanocomposite against human pathogenic bacteria was tested by disc diffusion method on Muller- Hinton agar medium. The pure HAp powder has excellent antibacterial activity and the antibacterial rate gradually rise with the increase in Copper and Zinc concentrations in the HAp nanopowders.