THE INFLUENCE OF ANXIETY AND DEPRESSIVE CONDITIONS ON AFTERINFARCTION REMODELING IN PATIENTS WITH STEMI
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.33, No. 33)Publication Date: 2017-06-30
Abstract
Epression after AMI increases the frequency of re-hospitalization because of acute coronary syndrome, heart failure, MI, and is a risk factor for cardiac arrest and death. The objective of the study was to define the influence of anxiety-depressive disorders (ADD) on afterinfarction remodeling and the participation of sST2 fibrosis factor in this process. 100 STEMI patients were enrolled to the study, 81 (81 %) male and 29 (29 %) female, of average age of 58,94 ± 10,16 years. Examinations were performed twice: during 1–3 days after PCI with infarct-related artery stenting and included clinical-anamnesis data, blood analyses. The sST2 level was defined by immune-fermentative method with usage of «Presage ST2 Assay», Critical Diagnostics, USA. For ADD objectivization, HADS (Heart Anxiety and Depression Scale) and Teylor questionary were used. In 6 month 6-minute walk test and the volume fraction of interstitial collagen (VFIC) were done. Conclusion: ADD in patients with STEMI aggravates the course of postinfarction period and entails the progression of fibrotic-hypertrophic processes and corresponding remodeling of myocardium, decrease of physical tolerance.
Other Latest Articles
- THE CONTENT OF MCP-1 AND MMP-9 IN BLOOD SERUM OF PATIENTS WITH CHRONIC POLYPOID RHINOSINUSITIS
- HEART RATE VARIABILITY PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION IN DEPENDENCE ON THE TYPE OF DAILY BLOOD PRESSURE PROFILE
- CHANGING OF THE DOSE COEFFICIENT OF THE MAJOR GROUPS OF DRUGS FOR PATIENTS WITH IMPLANTED PACEMAKERS, DEPENDING ON THE STAGE OF HYPERTENSION
- CHANGE OF NON-SPECIFIC FACTORS OF IMMUNITY UNDER INFLUENCE OF INTERFERON INDUCTOR (CYCLOFERON) IN BRONCHIAL ASTHMA IN CHILDREN
- E-Learning and E-Content Creation in India through Blended Learning
Last modified: 2017-09-12 02:14:01