SYNTHESIS OF 2, 5-DISUBSTITUTEDAMINO-2-THIO-1, 3, 5- THIADIAZOLES

A novel series of 2,5-disubstitutedamino-2-thio-1,3,5-thiadiazoles (Xa-g) was synthesized by the oxidative cyclisation of 1-substitued-thioamido-5-formamidinosubstituedthioamido-2-imino-4-thiabiurates (VIIa-g) in ethanol using iodine as oxidizing agent. The products were isolated characterised and justified on the basis of elemental analysis, chemical characteristics, and spectral studies. Keywords:1-substitued-thioamido-5-formamidinosubstituedthioamido-2-imino -4-thiabiurates and chloroform, microwave.