Comparative study of HbA1c level among iron deficiency diabetic patients with non-iron-deficiency diabetic patients among karaikal population

Introduction: Iron deficiency anemia is the most common form of anaemia in India. Haemoglobin A1c (HbA1c) is used in diabetic patients as an index of glycemic control reflecting glucose levels of the previous 3 months. Glycosylated hemoglobin (HbA1c) is used as a gold standard for monitoring glycemic control and as a predictor of diabetic complications. Conditions that affect erythrocyte turnover affect HbA1c concentration. Although many forms of anemia are associated with lowering of HbA1c, iron deficiency anemia tends to increase HbA1c. Aim of the study: To Compare the Hba1c Level and hemogram levels among Iron Deficiency Diabetic Patients With Non-Iron Deficiency Diabetic patients. Materials and methods: 25 Non-iron deficiency diabetic patients (controls) and 25 iron deficiency age matched diabetic patients (cases) with good glycemic control were enrolled in the study. Absolute HbA1c levels were measured in both the patients. The levels of hemoglobin, mean corpuscular hemoglobin (MCH), hematocrit, mean orpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), were measured by an automated counter these values were compared with those in the control population. Results: The mean baseline HbA1c level in iron deficiency diabetic patients (8.60) was significantly higher than that of controls (4.48) however, after 3 months of iron deficiency treatment, a significant decline from 8.60 to 6.5. Conclusion: Our study proved that iron deficiency anemia has a straight forward correlation with HbA1clevel in diabetic patients Moreover, with correction of iron deficiency in the anemic diabetic patients and HbA1c levels decrease.