EVALUATION OF CLINICAL INSTRUMENTAL AND LABORATORY PARAMETERS IN PATIENTS WITH FISTULA RECTUM WITH DIABETES MELLITUS

To evaluate the clinical, instrumental and laboratory parameters of blood in patients with fistulas of the rectum in combination with diabetes. Materials and methods. A comparative analysis of clinical and laboratory parameters and surgical treatment of 58 patients with fistulas of the rectum in combination with diabetes (study group) and 60 patients – with fistulas of the rectum without diabetes mellitus (control group) who were hospitalized in the department of Coloproctology GKB №5 Dushanbe from 2010 to 2015. Results. In patients with fistulas of the rectum in combination with type II diabetes mellitus revealed the predominance of patients aged 40 years and older. Among the patients was dominated by males – 43 (74.13%) of the main group, 48 (80.0%) in the control group. In both groups of patients was dominated by patients with rectal fistula transsphinktus and amounted to 46.5% and 50%, respectively. Ekstrasphinktal (24.2%) and recurrent (29.3%) – were predominant in patients with diabetes. Laboratory parameters of blood in patients with fistulas of the rectum in combination with diabetes differ and exhibits a decrease in the number of white blood cells, lymphocytes, monocytes, neutrophils and segmented blood. Moreover, in this group of patients showed increase of eosinophils in 39 (67.2%) of 58 patients with CRP and blood level of 55 (94.8%) cases. Conclusions. By age and sex and form fistula rectum showed no specific changes in individuals with diabetes. Insufficiency of anal sphincter in patients with fistulas of the rectum in combination with diabetes is mixed. In most cases, patients with fistulas of the rectum with diabetes type II marked decrease in the number of white blood cells, lymphocytes, monocytes, neutrophils and segmented blood, and increase in eosinophils and CRP levels of blood that can be used to assess the severity of diabetes complications and prognosis of progression. The incidence of cicatricial skin changes adrectal fiber and anal sphincter greater in patients with fistulas of the rectum on the background of diabetes than without it.