A CASE OF CAECAL GIST- RARE COEXISTENCE WITH ABDOMINAL TUBERCULOSIS

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumours of the gastro intestinal tract. The frequency of their location on the caecum is quoted with values lower than 10 of all GIST. Nearly 95 of GIST are positive for the CD 117 antigen, an epitope of KIT receptor tyrosine kinase expressed by their cell of origin, the Interstitial Cells of Cajal (ICC). Immunohistochemistry for CD117 is completely negative in approximately 5 of GISTs, though the morphological, molecular and the cytogenetic features are the same. Tuberculosis can involve any part of the gastrointestinal tract and is the sixth most frequent site of extra pulmonary involvement. The most common site of involvement of the gastrointestinal tuberculosis is the ileocaecal region which can present as a palpable mass in the right lower quadrant andor complication of obstruction.