The Effect of Erythropoietin on Salpingitis during Ischemia Reperfusion Injury in Rats
Journal: Austin Journal of Reproductive Medicine & Infertility (Vol.2, No. 5)Publication Date: 2015-08-10
Authors : Tsompos C Panoulis C Τοutouzas K Ζografos G; Papalois A;
Page : 1-5
Keywords : Ischemia; Erythropoietin; Salpingitis; Reperfusion;
Abstract
Purpose: This experimental study was to examine the effect of erythropoietin in a rat model and particularly in an oviducts Ischemia Reperfusion (IR) protocol. The effect of that molecule was studied pathologically using mean Salpingitis (S) lesions scores. Methods: 40 rats of mean weight 247.7 g were used in the study. Salpingitis lesions were evaluated at 60 min (groups A and C) and at 120 min (groups B and D) of reperfusion. Erythropoietin was administered only in groups C and D. Results: Epo administration non-significantly altered the salpingitis scores by 0 without lesions (p= 1.0000). Reperfusion time non-significantly altered the salpingitis scores by 0 without lesions (P= 1.0000). Furthermore, Epo administration and reperfusion time together non-significantly altered the salpingitis scores by 0 without lesions (p=1.0000). Conclusion: Epo administration interacted or not with reperfusion time nonsignificantly short-term altered the salpingitis lesions scores. Perhaps, a longer study time than 2 hours may reveal more significant effects.
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