A CASE REPORT ON KARTAGENER’S SYNDROME
Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 11)Publication Date: 2017-11-01
Authors : Mara Kurian Meekha Mary Varghese Haritha B Nair Navya Sunil Lubna Sulthana Hemalatha S Sivakumar T;
Page : 4566-4568
Keywords : primary ciliary dyskinesia; situs inversus; bronchiectasis; dextrocardia;
Abstract
Kartagener's syndrome is a rare congenital disorder consisting of situs inversus, bronchiectasis and sinusitis. It is a subgroup of immotile cilia syndrome called primary ciliary dyskinesia. In this syndrome generally male patients show infertility and reduced fertility in females. Mutation in DNAH5 gene located on chromosome 5p is responsible for this Mendelian disorder. Clinical manifestation involves recurrent respiratory infections and variability with multisystem involvement. Routine radiological tests are usually used for diagnosis. Prompt diagnosis and ideal management can prevent complications. Keywords: primary ciliary dyskinesia, situs inversus, bronchiectasis, dextrocardia
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