Treatment of Intraosseous Cystic Lesions of the Mandible by Conservative Enucleation and Cavity Filling with Allogenic Freeze-Dried Bone Mixed with Autologous Bone Marrow

Purpose: The aim of this study was to evaluate the outcome of defect filling with allogenic freeze-dried bone mixed with bone marrow following conservative enucleation of large intraosseous cystic lesions of the mandible. Patients and Methods: Forty-two patients with large intraosseous cystic lesions of the mandible were treated by defect filling with allogenic freeze-dried bone combined with bone marrow following conservative cyst enucleation. Results: All patients showed satisfactory healing. Dental rehabilitation including prosthesis and implant provision was successful in 10 (23.8%) patients. The patients were followed for 13-48 (mean, 29.9) months using panoramic radiographic examination. Recurrence was seen in 2 (11.2%) patients with KCOTs. Clinical and panoramic radiographic examination showed no residual or recurrent cyst in the remaining patients. Conclusion: Allogenic freeze-dried bone mixed with autologous bone marrow may be as an alternative, viable filling material for intraosseous cystic lesions of the mandible removed by conservative enucleation.