QUALITY CONTROL ANALYSIS AND ASSESSMENT OF DIFFERENT MARKET BRANDS OF CIPROFLOXACIN

Dose structures are basically pharmaceutical items in the structure in which they are showcased for use, normally including a blend of dynamic medication parts and nondrug segments (excipients), alongside other non-reusable material that may not be considered either fixing or bundling, (for example, a container shell, for instance). The term unit measurements can now and then envelop non-reusable bundling too (particularly when every medication item is exclusively packaged. Different measurements structures might exist for a solitary specific medication, since various medicinal conditions can warrant distinctive courses of organization. For instance, steady queasiness and heaving might make it hard to utilize an oral dose structure, and in such a case, it might be important to use a backup course of action, for example, inhalational, buccal, sublingual, nasal, suppository or parenteral. The primary objective was in vitro comparative study of 5 different brands of Ciprofloxacin Tablets available in markets of Pakistan by The in vitro comparative study of 5 different brands of Ciprofloxacin Tablets available in markets of Pakistan Weight variation Test, Disintegration Test, Hardness Test, Chemical Assay and In vitro dissolution study was conducted. After conducting color, friability, weight variation, hardness test and disintegration tests of various brands of Ciprofloxacin, the results were found under the acceptance range. The hardness showed variation among the tablets of various brands but there was no significant variation of hardness among the tablets of same brand. The Axcin indicated maximum drug potency (102%) and (101%) respectively while minimum potency was 93.07%. The in-vitro evaluation of 5 different F.P.Ps of Ciprofloxacin HCl film coated tablets available in the pharmaceutical market of Pakistan showed that all of brands of Ciprofloxacin satisfied the USP potency specifications and showed evidences of satisfactory initial in-vitro dissolution behavior.