FACTORS INFLUENCING DEVELOPMENT OF TUBERCULOSIS IN HIV - INFECTED PATIENTS IN DUSHANBE CITY

The incidence of HIV/TB in the city of Dushanbe over the period 2006-2013 was evaluated and the conditions influencing tuberculosis formation in HIV-infected patients in Dushanbe were studied. The analysis of outpatient cards and 52 case histories of patients treated in the City Infectious Diseases Hospital shows that the most important factor in the development of tuberculosis in HIV-infected patients is the presence of HIV infection, factors such as migration, smoking, drug use especially injecting and the presence of tuberculosis in the family. It was found out that in Dushanbe, TB and HIV / AIDS epidemics develop independently, and in the vast majority of TB patients, the disease is not accompanied by immunosuppression, characteristic for patients with HIV infection. The risk of TB in people living with HIV is significantly higher in those regions where its prevalence is higher. The relative tense epidemiological situation in the city of Dushanbe is characterized by the annual growth rate of patients with co-infection of tuberculosis and HIV because of the difficulty of diagnosis in the early stages of TB infection and with the negligence of the patients themselves for timely and full treatment. Significant risk factors for the development of tuberculosis in HIV-infected patients are also worsening socio-economic living conditions of the population, increasing migration processes, smoking, drug use, especially injecting, and contact in the family with a sick tuberculosis.