Logical Models Using Boolean Network to Study Breast Cancer Signalling Pathways
Journal: International Research Journal of Advanced Engineering and Science (Vol.2, No. 4)Publication Date: 2017-11-20
Authors : Sanchari Chatterjee;
Page : 185-188
Keywords : ;
Abstract
The transformation of biological gene to a similar synthetic form is subjected to investigation of vulnerable components in a signaling pathway which contribute the development of drug therapy pointing out towards the aberrations in that pathway. Logic models were thus developed for analyzing the vulnerability of the components in multiple signaling pathways. The heterogeneities in signaling pathways among the patients address the different response of breast cancer from patients to patients. The targets accepted universally are those, whose vulnerabilities are invariably high among the others
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