EFFECT OF EXPERIMENTAL FASCIOLOSIS AND DIETHYLNITROSAMINE INTOXICATION ON TRACE ELEMENTS CONTENT IN RAT LIVER

The aim of the work was to be investigated the trace elements content in rat liver after the effect ofchronic fasciolosis and diethylnitrosamine (DENA) intoxication. The Mo, Rb, Br and Cu contents were near tothe controls or slightly increased. The highly increased quantity of Cu and low values of Zn, Fe and Co wereestablished. The obtained results pointed that the combined action of Fasciola hepatica and DENA leaded to aspecific mineral imbalance in the liver, which might take place in the pathogenesis of the interaction betweenexperimental fasciolosis and chemical intoxication.