QUALITATIVE ANALYSIS AND α-AMYLASE INHIBITION ASSAY OF AQUEOUS FOLIAR EXTRACT OF SYZYGIUM CUMINI (L.)

Syzygium cumini is one of the important medicinal plants found in all parts of India. Syzygium cumini (L.) is commonly known as jambolan, Java plum or black plum. It is an evergreen tropical flowering plant belongs to family Myrtaceae. This plant has many pharmaceutical activities such as anti-diabetic, anti-oxidant, CNS depressant and etc. The present study was carried out on foliar extract of Syzygium cumini to find their significance in diabetic therapeutic studies. The conducted work was based on phytochemical analysis and in-vitro α-amylase activity. High concentration of glucose in the blood causes a metabolic disorder which is known as diabetes. High concentration of glucose in blood may damage many of the body's systems that is why diabetes is a chronic disease. The result of qualitative analysis exhibited that this plant contains alkaloids, flavonoids, saponins and phenol in leaves but amino acid was absent. The phytochemicals present in plants are responsible for preventing disease and promoting health have been studied extensively to establish their efficacy to understand the underlying mechanism of their action. The result of this study revealed that leaves extract showed α-amylase inhibition in a dose-dependent manner. The extracts showed maximum inhibition at a concentration of 1 mg/ml and which is decreased with increasing concentrations i.e. 2.5 and 5 mg/ml. In conclusion, more research is required for developing a potential and valuable antidiabetic therapy by using α- amylase inhibition. Keywords: Α-Amylase Inhibition, Foliar Extract, Syzygium Cumini (L.)