TO STUDY THE EFFICACY OF ORAL MIDAZOLAM AS A PRE-MEDICATION FOR CHILDREN POSTED FOR GENERAL ANAESTHESIA

Introduction: The major objectives of preanesthetic medication are to decrease the stress response with preservation of hemodynamic parameters, facilitate anaesthesia induction and produce amnesia. Preoperative anxiety is a common phenomenon in children. Midazolam is commonly used in children and has been demonstrated to be a very good sedative, anxiolytic and amnesic premedicant. Midazolam is absorbed rapidly and completely after oral administration. Methods: Aim of the study was to study the effectiveness of oral Midazolam as premedication of paediatric patients undergoing surgery under general anaesthesia with respect to: Ease of separation from parents, degree of sedation achieved (sedation score) preoperatively and postoperatively and patient?s co-operation for venipuncture. Material and method: The study was carried out in department of anaesthesiology JNMC and AVBRH Savangi, Meghe, Wardha, during 2016-2018 after taking prior permission from institutional ethical committee. It comprised of 60 subjects. They were randomly allocated to 2 groups. Group A - patients received 0.5mg/kg body weight oral Midazolam, Group B ? patients received 1.0mg/kg body weight oral Midazolam Results: 1 mg/kg body weight dose gave better results than 0.5mg/kg body weight dose in terms of ease of separation from parents and co-operation for venepuncture. Conclusion: 0.5mg/kg and 1mg/kg body weight doses of oral Midazolam can be safely administered as premedication to paediatric patients but 1 mg/kg body weight dose is more effective as a pre medication for children posted for General Anaesthesia.