DEVELOPMENT OF A FUNCTIONAL BASIS OF PHYTO-BEVERAGES WITH AN INCREASED ANTIOXIDANT ACTIVITY FOR THE CORRECTION OF NUTRITION OF PATIENTS WITH DIABETES MELLITUS

Diabetes mellitus is the most threatening form of human metabolic disorder and of malnutrution as one of the main causes of its development. The purpose of the studies is the development of a functional basis of phyto- beverages based on herbal medicinal raw materials with a high antioxidant activity for the correction of nutrition for diabetic patients. The object of the studies was plant medicinal raw materials that grow mainly in the territory of the Kemerovo region, various vegetative parts of plants were used: leaves (of cranberry, knotgrass, common St. John's wort, blindweed, common plantain and common horsetail); roots (of elecampane, common burdock, common dandelion); valves (common beans); shoots (of blueberry). The antioxidant activity of water extracts from plant raw materials mixtures was determined using a spectrophotometric method based on the determination of concentration of malonic dialdehyde in biological material. The following compositions of mixtures have been experimentally determined: 1) common St. John's wort, great nettle, common dandelion, blueberry, common horsetail; 2) knotgrass, great nettle, blueberry, common horsetail; as well as the following extraction parameters: the degree of grinding of raw material is 5-8 mm, the ratio of solid (medicinal plant raw material) and liquid (water) phases is 1 : 7, the temperature is 50 ± 1C, the extraction time is 6 hours. A possibility of preserving finished extracts with alcohol up to 8% of the volume fraction has been determined, which allows to keep them for 30 days providing the alcohol content in the beverage on the basis of the extract of not more than 0.5%, according to the applicable requirements. It has been shown that the created extracts have an antioxidant activity.