PHILADELPHIA CHROMOSOME POSITIVE CHRONIC MYELOGENOUS LEUKEMIA IN CHILDHOOD:A RARE CASE REPORT
Journal: Era's Journal of Medical Research (Vol.04, No. 01)Publication Date: 2017-06-01
Authors : Kshama Tiwari Sharique Ahmad Kshitij Tewari Amrisha Jaiswal Sania Zahra Rizvi Syed Riaz Mehdi;
Page : 73-75
Keywords : Chronic Myelogenous Leukaemia; Philadelphia Positive Cml; Clonal; Hematopoietic Stem Cell Disorder;
Abstract
CMLis a clonal hematopoietic stem cell disorder. As per WHO classification, CML is included in Myeloproliferative disorder. Adult type - CML is rare in childhood constituting about 3% of childhood leukaemia. We have reported such a case in a 7yr old male child. Peripheral blood smear and bone marrow revealed features of chronic myeloproliferative disorder and cytogenetic analysis has proved Ph chromosome positivity. We report one such case of Philadelphia positive CMLin a 7 year old male patient with chief complaints of fever on & off since 4-5 months and sense of abdominal fullness since 1 month, on examination pallor was found with mild hepatomegaly and moderate splenomegaly. The clinical differential diagnosis was malaria, storage disorder or tropical splenomegaly. Though biological behaviour and prognosis are identical to that of adult type, we are reporting this case because of its extremely uncommon incidence.
Other Latest Articles
- A PEDAGOGICAL APPROACH FOR ENGINEERING EDUCATION
- MINIMIZING AND MAXIMIZING OF ENCODED IMAGE BY WAVELET TRANSFORM
- MAYER-ROKITANSKY-KUSTER-HAUSER (MRKH) SYNDROME WITH BEHAVIOURAL DISTURBANCE AND MENTAL RETARDATION: A CASE REPORT
- SMART ATTENDANCE AND LIVE LOCATION MAPPING USING UHF RFID
- ABERRANT FORM OF KLEBSIELLA PNEUMONIAE IN FULMINANT EMPHYSEMATOUS HEPATITIS WITH POLYMICROBIAL INFECTION
Last modified: 2018-04-20 14:42:33