AN EPIDEMIOLOGICAL SURVEY ABOUT THE INFECTIONS CAUSED BY DENGUE IN THE PERSPECTIVE OF HEMATOLOGICAL, CLINICAL AND DEMOGRAPHIC RISK FACTORS

Objective: Our research determines the patients in terms of their clinical, demographic and hematological factors of dengue infection risk specifically in the rural communities of lower classes in 2016-17 outbreaks in Karachi. Methods: We conducted research for the data collection of clinical and epidemiological nature for the infection of dengue in the less privileged communities. The outcomes of Dengue fever, Dengue Shock syndrome and Dengue hemorrhagic fever were verified through IgM and IgG anti bodies detected through Enzyme-linked immunosorbent assays (ELISAs) method which was based on the WHO criterion. A total of 350 patients were selected through random cluster sampling method. Research was continued after ethical approval and consent of the participants. SPSS-21 was used for the data analysis. Chi-Square was applied for the categorical variables determinations. Results: In the total research sample 105 participants (30%) were rural affected cases, dengue fever was observed in 58 participants (16.6%), 30 patients (8.6%) were observed with dengue hemorrhagic fever and remaining 17 participants (4.9%) suffered from dengue shock syndrome. In the course of treatment 12 participants died, every case presented the manifestations of cutaneous and fever. Significance presence was observed in the severe pain, married and educated cases with a p-value of (0.001). Conclusion: Thirty percent cases of dengue infection were noticed in the survey while visiting the endemic areas. Associated factors of risk were severe pain, five-year education, unmarried and female cases. Patients also presented febrile illness with clinical features and hematological observations about the dengue fever. Keywords: Dengue fever, Clinical Pattern, Dengue Hemorrhagic Fever, Epidemiology, Community and Surveillance.