A Prospective Observation Study of Adverse Drug Reactions Due To and Medical Related Problems in the Treatment Chart Prescribed by Registered Medical Practitioner

Adverse drug reactions (ADR'S) are defined as the injury caused due to medications by a single drug or multiple drug with the prolonged administration and in some conditions which are not identified with the drug. Materials and Methods: Study Method: It was a prospective observational study carried out in the rural areas. Study Site: The study was conducted in rural areas in and around Karimnagar with having minimum of 2700 houses. Study Procedure: The study was done by collecting the information by using a HRQOL and WHO Questioner. Nearly considered 1800 people out of which 720 people are interested to give their information about health conditions and the use of drugs Sample Method: All patients of age between 18-60 years were included in the study Study Duration: The study was conducted for 12months from august 2016 to august 2017. Inclusion Criteria: The people who are willing to give information. People of both sexes. Who are above the age of 18-60 suffered with any type of illness. Medications used given by the RMP. Exclusion criteria: Who are not willing to give the information. Pregnancy and lactating mothers. Of sane minded. Aging below 18 years. Study Material: Patient Consent Form: Consent was collected by using self design consent form and was made into 3 languages. Ethical Approval: The study was approved by institutional ethical committee and tertiary care hospital. Data Analysis: A data was analyzed by different statistical software's in which the information is analyzed by using Microsoft excel 2007 and results were given in percentage. Results: A total of 1800 people 720 are willing to fill the questionnaire regarding the RMP visits, conditions, medications used and treatment outcomes are discussed below. Discussion: Out of 1800 people of rural area only 720 people are willing to give the information out of which the age group 18-60 (100%) of both sexes (100%). In this most of the people are unmarried with educational level of primary and Nutrional status of average and poor with average hygienic conditions and maximum are daily wage labour 420 (58.2%). The main reasons for visiting RMP is fever 706 (98.10%), cold 685 (95%), cough 685 (95%) and skin infections 368 (45%) and the drugs mainly prescribed by RMP's are paracetmol 185 (10.2%) and ranitidine 197 (10.9%). The different classes of drugs prescribed were mainly antibiotics and the people mainly suffered with headache 97 (13.4%) and abdominal pain. Common ADR's observed with single or multiple drugs are mainly dehydration 321 (44.58%), asthma 154 (21.38%) and in which the ADR's identified by family members or RMP are mainly fatigue 315 (43.75%) and vomiting. ADR's assessed by clinical pharmacist using Naranjo scale is mainly mild 135(72.29%). The ADR's after the treatment by RMP is mainly 0 and 1 ADR's, the treatment of RMP is no response is 325 (45.13%) and death of 2 patients and the survey was taken from nearby villages, mainly thimmapoor are more interested to visit to RMP than primary hospitals. Conclusions: Our study concluded that most of the people in the rural areas mainly consult RMP's due to their low educational and economically backward people. The RMPs prescription contains many ADR's with unknown knowledge about the disease and drugs. It leads to many complications and serious events can takes place by the prescription.