A Review on Gas Gangrene and its Management
Journal: PharmaTutor (Vol.2, No. 5)Publication Date: 2014-05-01
Authors : M Sushma; TVV Vidyadhar; R Mohanraj; M Babu;
Page : 65-74
Keywords : Gas Gangrene; Clostridial myonecrosis; Maggot therapy; Antibiotics; Oxygen therapy;
Abstract
Gas gangrene is described as an infection of muscle tissue by toxin-producing clostridia. Gas gangrene is also known as “Clostridial myonecrosis”, gained recognition for its wartime incidence, during which only a paucity of civilian cases occurred during wars. Blood is major component in which its absences favour the development of gas gangrene. Such conditions were seen in the cases like atherosclerosis, diabetes, peripheral arterial disease. Depending on this blood supply and attack of infection the gas gangrene can be classified into Dry gangrene and Wet gangrene. This gas gangrene presents clinically with Dry and Cold skin with Pain and Swelling associated with Blisters. There are a typical causes and pathogenesis involving different type of toxins for the formation of gas gangrene. The treatment is approached by using a type of Maggot therapy, Antibiotics, Oxygen therapy. Surgery also preferred in the treatment.
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Last modified: 2014-05-14 17:35:21