Effect of Allium sativum (Garlic) Extract on Blood Coagulation and Fibrinolysis

The present study was aimed to evaluate the effect of Allium sativum (Garlic) extract on coagulation of blood and fibrinolysis of blood clot. Capillary tube method was used to estimate the clotting time of blood. 20 healthy human volunteers were included in this study and acted as self control. The variation in the clotting time of blood in presence of various doses of garlic extract was estimated. The results of the present study showed that anticoagulant property of the extract. It was also found the fibrinolytic activity of the extract may be by preventing or prolonging the time required for clot formation by altering the coagulation mechanism.