Investigation of Phytochemical Profile and Combine Synergistic Anti-Diarrheal Potential of Peperomia Pellucida Aerial Part and Cyprus Esculentus Root Extracts
Journal: Open Access Journal of Pharmaceutical Research (Vol.1, No. 7)Publication Date: 2017-10-04
Authors : Majumder P;
Page : 1-8
Keywords : Peperomia pellucida; Cyperus esculentus; Tannins; Castor oil induced diarrhoea; Antidiarrhoeal;
Abstract
Peperomia pellucida and Cyperus esculentuslocally found plant used for anti-diarrhoeal activity using standard animal model. The aerial parts of Peperomia pellucidaand Cyperus esculentuswere collected from Trikaripur forest area, kasaragod district of Kerala, India, dried and extracted with ethanol (70%). Wistar albino rats were used for studies. Castor oil was used to induce diarrhoea and 200, 400 mg/kg of ethanol extract of Peperomia pellucida and Cyperus esculentus dual combination was used to test antidiarrhoeal activity. Results were calculated by student âtâ test, to assess statistical significance.The extract showed dose dependant inhibition of frequency of defecation as well as reduction in number of wet feces. The percentage inhibitions of faecal with 200 and 400 mg/kg doses of ethanol extract were 69.15 and 76.21 respectively. The plant extracts contains tannins and flavonoids, which could have contribution to the antidiarrhoeal activity. Peperomia pellucida and Cyperus esculentuscombine hydro-ethanolic extractpossesses significant antidiarrhoeal activity compared with loperamide.
Other Latest Articles
- EFFECTIVENESS OF SPECIFIC NURSING INTERVENTION PROGRAME ON MOTIVATION AND RELAPSE AMONG CLIENTS WITH ALCOHOL DEPENDENCE SYNDROME-A PILOT STUDY
- MISOPROSTOL INDUCTION OF LABOR IN MULTIPARA PREGNANT WOMEN: A MINI-SURVEY FOR PREDICTORS OF OUTCOME
- Development and Validation of RP-HPLC Method for Simultaneous Estimation of Moexipril and Hydrochlorothiazide in Bulk and Tablet Dosage Form
- Food Geographies, Some Considerations in the Current Research Trends
- Introducing Paddy (Oriza sativa) in the Plantation Forest Management to Support Food Safety
Last modified: 2018-05-26 18:04:37