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A RARE CASE REPORT ON LANGERHANS CELL HISTIOCYTOSIS(LCH) IN A 4 YR OLD CHILD

Journal: International Journal of Advanced Research (Vol.6, No. 4)

Publication Date:

Authors : ;

Page : 1354-1356

Keywords : Langerhans cell histiocytosis Histiocytosis X APC.;

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Abstract

Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, is an uncommon haematological disorder affecting infants and young children. It is a condition characterized by uncontrolled stimulation and proliferation of normal antigen presenting cells (APC), Langerhans cells. Its aetiology is unknown but it could be due to antigenic stimulus of an infection, genetic abnormality, deregulated immune response, or even clonal origin. Clinical presentation may be localized or systemic, invading skin, lungs and bone in adult, and bone marrow and lymph node in children. The purpose of this paper is to report a case of LCH in a 4yr old child with multisystem involvement.

Last modified: 2018-05-28 20:22:10