Metabolomics - the new "omics" of health care
Journal: Journal of Clinical and Scientific Research (Vol.1, No. 3)Publication Date: 2012-07-01
Authors : V.S. Kiranmayi; P.V.L.N. Srinivasa Rao; Aparna R. Bitla;
Page : 131-137
Keywords : Metabolic disorders; Metabolomics; Health care;
Abstract
Metabolic diseases are caused by chronic dysregulations of metabolism that differ among individuals due to interactions of the genetic and environmental influences manifesting as a particular phenotype. These are usually diagnosed with the help of individual metabolites which serve as disease biomarkers. However, single biomarker based diagnostics for metabolism-based diseases fails to identify the cause of the alteration of these surrogate markers. This is where metabolomics comes into the clinical picture as it not only helps in assessing the risk of an individual for developing a particular disease but also helps in individualizing therapy based on the metabolic defect. Metabolomics is named in line with other recently developed approaches of diagnostics, i.e., genomics and proteomics. This review provides an overview of the fundamental basic principles, the techniques involved and the applications of this new -omics of healthcare.
Other Latest Articles
- Impact of Socio-Economic Status on Age at Menarche
- High sensitivity C-reactive protein levels across spectrum and severity of coronary artery disease
- Study of Nano-Particle based Pesticides as an Alternative to Conventional Pesticides
- Pan-resistance among gram-negative clinical isolates at a tertiary care hospital in south India
- Brand Personality in Rural Area- A case study of FMCG in Vidisha District of Madhya Pradesh
Last modified: 2014-05-22 18:50:17