Case Report: Severe Lower Extremity Contour Defect Correction with Cell - Assisted Lipotransfer and Flap

Here we report on a case involving a novel approach to correction of a severe lateral thigh contour defect resulting from necrotizing fasciitis. Cell - assisted lipotransfer (CAL), a promising technique in which lipoaspirate fat graft is enhanced with pluripotential adipose stem cel ls, was used in this case to replace deficit soft tissue volume in conjunction with advancement flap closure of the skin defect. The use of cell enhanced lipotransfer with excision and closure of the defect allowed a complete and permanent restoration of s oft tissue volume in a one stage procedure. The one stage procedure was well - tolerated, and the patient experienced restored mobility, diminished pain, and improved cosmetic appearance compared to improvement expected from advancement flap closure alone. T his report demonstrates the utility of CAL to supplement difficult and complex one stage reconstruction cases.