Study of the polymorphism of the aroe gene in Kabardino-Balkarian Republic residents of the senior age group
Journal: Science Journal "NovaInfo" (Vol.2, No. 86)Publication Date: 2018-06-16
Authors : Otroshchenko Irina Nikolaevna; Sitnikov Maksim Nikolaevich;
Page : 13-17
Keywords : POLYMORPHISM; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASES; LIFE EXPECTANCY; APOLIPOPROTEIN; APOE GENE;
Abstract
The study of polymorphism of the APOE gene in the population of the Kabardino-Balkarian Republic of the older age group was carried out. The predominance of the E4 / E4 genotype over the heterozygous genotype E3 / E4 is shown. The frequencies of alleles of the APOE gene differ slightly from those of the West European population, which is related to the specific composition of the sample. A positive relationship between the level of cardiovascular diseases and the genotypic structure of the sample was established.
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