Invasive yeast infection in patient with Acute pancreatitis

The incidence of invasive yeast infections is rising in patients hospitalised in intensive care. Their early diagnosis is problematic, although predictive models (Pitt's colonization index, Leon score and others)can be helpful when deciding to initiate treatment. The incidence of candidiasis signifi cantly increases the mortality of patients, although the timely commencement of antimycotic therapy is a key factor in increasing their survival. In the present patient, antibiotic treatment with carbapenem was initiated after CT verifi cation of necrosis with formation of abscesses and the onset of infl ammatory parameters. After surgical review, septic shock developed with multi-organ failure. Microbiological examinations of biological materials also revealed non-C. albicans yeast was present in haemocultures, so echinocandin and anidulafungin were included in the treatment. C. parapsilosis persisted in haemocultures, while negative haemoculture was obtained 14 days after the inclusion of iposomal amphotericin B.