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Bleeding Risk under Oral Factor Xa Inhibitors: Meta-analysis of the randomized comparison with Vitamin K Antagonists and Meta-Regression analysis

Journal: Journal of Cardiovascular Medicine and Cardiology (Vol.4, No. 3)

Publication Date:

Authors : ; ;

Page : 038-048

Keywords : Oral Anticoagulants; Factor Xa Inhibitor; Antivitamin K; Bleeding Events; Major Bleeding; Gastrointestinal Bleeding; Intracranial Haemorrhage; Atrial Fibrillation; Meta-Analysis;

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Abstract

Background: Randomized trials have shown that oral direct factor Xa inhibitors (ODIXa) offer potential advantages over vitamin K antagonists (VKAs). It is however unclear whether the magnitude of their benefi t is similar at the current recommended doses.

Last modified: 2018-09-05 15:22:11