Basement membrane in health and disease- an enigma to histopathologist
Journal: Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology (Vol.4, No. 2)Publication Date: 2018-06-01
Authors : Vijaykumar Biradar Namita Shrivastav Priya Shree Rakhee Sinha Akhilanand Chaurasia;
Page : 100-105
Keywords : Basement membrane; Extracellular matrix; Health; Disease;
Abstract
Basement membrane is known to play a role in the pathogenesis of inflammatory, tumor invasion, metastases and autoimmune diseases. A basement membrane (BM) is a thick sheet of extracellular matrix molecules, upon which epithelial cells attach and form a boundary between epithelium and the connective tissue. It also provides structural support for epithelial, mesothelial, and endothelial cells and surrounds adipocytes, muscles and Schwann cells. This literature review describes terminologies, histology, ultrastructure, molecular aspects, functions and histochemical studies of basement membrane in health and disease.
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Last modified: 2018-09-07 18:29:06