SPECTRUM OF MICROFLORA IN URINE OF PATIENTS WITH CHRONIC RECURRENT PYELONEPHRITIS (THE TEN YEARS FOLLOWING-UP)

The aim of this work was to compare the specific spectrum of bacterial pathogens which stipulate chronic recurrent pyelonephritis during the longitudinal following-up. Materials and methods. There were performed the complex microbiologic investigations of urine, scrapes from cervical canal and vaginal smears from 386 women with chronic pyelonephritis. Results. The analysis of the spectrum of microflora separated out of the patients' urine during 10 years showed the considerable growth of the specific weight of Enterococcus spp. (up to 18,6 %). In the process of chronic pyelonephritis recurrence in 64,3 % patients showed the changes in the specific spectrum ofpathogens with the prevalence of E.faecalis and S.epidermidis (14,3 % each). At the same time, there was stated the presence of opportunistic microflora in vaginal smears (40,1 %) and scrapes from cervical canal (30,8 %) of the examined women. The mechanism of bacteria persistence in urogenital tracts in women with chronic recurrent pyelonephritis was also under study. Conclusion. There has been confirmed the importance of the comprehensive study of the spectrum and specificity of pathogens which can stipulate the aggravation of chronic pyelonephritis and mechanisms of its course.