Correlation between Dysbiosis of Gut Microbiota and Human Colorectal Cancer
Journal: International Research Journal of Advanced Engineering and Science (Vol.3, No. 3)Publication Date: 2018-08-28
Authors : Chae Rin Oh;
Page : 226-231
Keywords : Gut Microbiota; Short-Chain Fatty Acids(SCFA); βGlucuronidase (β-G); Beneficial Bacteria; Harmful Bacteria; Gastrointestinal Tract. Symbiosis; Dysbiosis;
Abstract
The exquisite balance between beneficial bacteria and harmful bacteria is maintained in the gastrointestinal tract. If meateating habits persist, the population of harmful bacteria that cause carcinogens increases in the human gut. Some carcinogenic substances are produced in tryptophan metabolism, which degrades proteins. Others are produced during the process of producing fatdecomposing bile. The beneficial bacteria stimulate the activation of immune cells and control the population of harmful bacteria. However, when the population of beneficial bacteria with the ability to regulate immune cells is reduced. At this time, the population of harmful bacteria increases sharply, it is generated carcinogenic agents causing colon cancer.
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