Unexplained Hoarseness of Voice after Radioactive Iodine Therapy; A Rare Complication

Hoarseness of voice is extremely rare after radioactive iodine therapy for Graves's disease. Here we report a case of 29 year old lady who received one dose of 15mCi of RAI. After one day she presented with severe hoarseness of voice, severe pain in neck and some sore throat. The pain and sore throat resolved after a week with NSAID therapy but her hoarseness of voice persisted. She underwent direct laryngoscopy twice but showed no abnormality in vocal cord. Later on her voice started to improve and by about 6 months largely recovered. This case is in addition to few rare case reports in medical literature in which RAI caused hoarseness of voice.