Prevalence of Zidovudine Induced Megaloblastic Anemia among Human Immunodeficiency Virus Positive Patients Attending University of Gondar Hospital Antiretroviral Therapy Clinic, Northwest Ethiopia

HIV infection is frequently associated with hematological abnormalities such as anemia which is increasing in frequency and severity with progression of infection to immunologic and clinical AIDS [1]. Typically the anemia may result from low production of red blood cells, increased RBC destruction, or ineffective RBC production and frequently the laboratory features are compatible with anemia of chronic disease with a low reticulocyte count, normocytic normochromic red blood cells with normal iron stores and cytokine mediated poor erythropoietin response [2, 3].